Bioinformatics Asked on December 20, 2020
I have been calculating the binding Affinity between a Ligand and a Protein using both AutoDock Vina and AutoDock tools but the binding affinity estimates obtained from the 2 molecular docking softwares are very dissimilar. For instance, in the example below the binding affinity estimated by AutoDock Vina is -12.6 but for the same Ligand and Protein the Binding Affinity according to AutoDock Tools is +158.0. Why would there be such a massive difference.
Thank you
2 Asked on August 21, 2021
1 Asked on August 21, 2021 by najeha-mohamed
1 Asked on August 21, 2021 by mariam
2 Asked on August 21, 2021 by felipe-almeida
1 Asked on August 21, 2021 by ace8910
1 Asked on August 19, 2021
4 Asked on August 19, 2021 by jameshfisher
2 Asked on August 19, 2021 by clove444
1 Asked on August 19, 2021 by ophelia-vallee
2 Asked on August 19, 2021
chip seq differential expression macs2 peak calling sequence analysis
0 Asked on August 18, 2021 by sasam
0 Asked on August 17, 2021 by unicorn
1 Asked on August 15, 2021
1 Asked on August 13, 2021
1 Asked on August 10, 2021 by beachwildernessgene
Get help from others!
Recent Questions
Recent Answers
© 2023 AnswerBun.com. All rights reserved. Sites we Love: PCI Database, MenuIva, UKBizDB, Menu Kuliner, Sharing RPP, SolveDir