How to import large .bed, .gff, .vcf, .paf, .sam files into an SQL database?

Are there best practices to load different bioinformatics file formats such as VCF, BED, GFF, and SAM to SQL databases? I am wondering how people out there do that efficiently.

All of these three formats are tab-separated files, so basically the following should work. I feel weird about it since most people I know don’t use MySQL to work with these files.

LOAD DATA LOCAL INFILE 'bed.bed' INTO TABLE bed-file FIELDS TERMINATED BY 't' LINES TERMINATED BY 'n' IGNORE 1 ROWS (list of the columns) SET creation_date  = STR_TO_DATE(@creation_date, '%m/%d/%y');