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Tool for rna/lna melting temperature prediction

Bioinformatics Asked on June 24, 2021

Is there any tool available to predict the melting temperature for rna/lna oligos with its perfect complement ?

I know this amazing website from qiagen/geneglobe that estimates the tm value.

But is there any command line tool that does this?

I can estimate the normal tm value with RNAcofold and the -T option but there is no lna option.

I searched for a while but i can only find online services.

One Answer

There are several programs for simulating/predicting DNA melting but you could try them for RNA. You can look here http://bioinformatics.org/meltsim/wiki/Main/HomePage.

Answered by 02213 The Godfather on June 24, 2021

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