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How does HIV know to attack specific immune system cells?

Biology Asked by Lewis on May 3, 2021

I’m no biologist, but curious of the answer to which I could not find online.

How are Human Immunodeficiency viruses able to detect and distinguish immune system cells with a CD4 receptor on the surface from other cells in the body, in particular other immune system cells without the receptor?

If I have asked the question on the wrong platform, please inform me otherwise.

Thanks

One Answer

The CD4 receptor is a protein complex that harbors very specific chemistry. A virus is able to bind with the receptor if it harbors a particular protein/set of proteins that are able to interact with the receptor. The virus is basically disguised as something the CD4 receptor recognizes, and from there it is internalized within the cell via a process called endocytosis. You can google viral endocytosis to learn more.

Correct answer by JMorrissette on May 3, 2021

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