What does NKX2-5 do?

Medical Sciences Asked on November 4, 2021

Where is the gene ‘NKX2-5‘ located and what is its function? How is it relevant to developmental disorders?

One Answer

In mammalian cells the gene NKX2-5 is found on chromosome 5, more specifically on the long (q) arm of chromosome 5 at position 35.1. (Cytogenetic Location: 5q35.1)

NKX2-5 is ~3,213 nucleotide bases long and is involved in biological processes that give an organism its shape. Disruption of NKX2-5 has proven to cause abnormal heart shape.

More information can be found: here

Answered by Andrew on November 4, 2021

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