How to say the difference between two things

How would one say "The difference between [object A] and [object B] is…" in Russian? For instance, I might want to ask "Do you know the difference between chinos and jeans?"

A quick google translate gives разница между

I thought that между was only used when describing where objects were situated spatially, but I also don’t know much of the language.

Is this even a natural way to speak in Russian? Or would it depend on the situation?