Restrict access to a drive to a single program (Windows)

I have a hard drive (not external) with incremental backups of my system and documents. The computer may be accessed by others in some cases, and they will be using the same account with admin privileges. Also, there are many other computers attached to the same network. All of this makes me a little worry for the data on the drive, be it in case of a human error, or worse in case of ransomware. Because I use the drive exclusively for backups, there’s no need for any user (including myself) or other programs besides the backuping app to access the drive. So I began to wonder, is there a way to limit the access to the drive to just one program in Windows?